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. 2021 May 16;21(10):3467. doi: 10.3390/s21103467

Figure 2.

Figure 2

(A) (a) Schematic of DNA biosensor based upon a graphene field-effect transistor funct-ionalized with complementary probe DNA. (b) Raman spectrum of the channel region of a graphene field-effect transistor (GFET) after processing. Inset: Optical micrograph of an array of 52 GFETs. (c) I-Vg characteristics for an array of 52 GFET devices showing excellent reproducibility. (d) Histogram of the Dirac voltage extracted from the I-Vg characteristics of the panel (b) along with a Gaussian fit to the data (red curve) [70]. Reprinted with permission from ref. [67]. 2016 American Chemistry Society. (B) Biosensor response to positive and negative controls. (a) Relative Dirac voltage shifts for various positive control experiments based upon concentrations of 1 μm for the target DNA and the specified helper DNAs. (b) Relative Dirac voltage shifts for 10 nm target DNA and negative controls with base mismatches at the ends; detailed DNA sequences are listed in Table S1. Error bars are the standard deviation of the mean. Helper DNAs were 1 μm. Reprinted with permission from ref. [65]. 2018 American Chemistry Society.