Table 1.
Examples of cancer types where expression of Fibroblast Growth Factor (FGF) subfamily members regulate oncogenic processes.
| FGF Subfamily | Cancer Type | Associated References |
|---|---|---|
| FGF1 | Bladder | [95] |
| Breast | [96] | |
| Melanoma | [97] | |
| Ovarian | [98] | |
| Pancreatic ductal adenocarcinoma | [99] | |
| Small cell lung cancer | [100] | |
| FGF4 | Bone | [101] |
| Gastrointestinal | [102,103] | |
| Glioma | [104] | |
| FGF7 | Breast | [42] |
| Gastric | [105] | |
| Non-small cell lung cancer | [106,107] | |
| Pancreatic ductal adenocarcinoma | [108] | |
| FGF8 | Colorectal | [109] |
| Hepatocellular carcinoma | [110] | |
| Head and neck | [111] | |
| Prostate | [112] | |
| Renal cell carcinoma | [113] | |
| FGF9 | Colorectal | [114] |
| Hepatocellular carcinoma | [115] | |
| Prostate | [116,117] | |
| FGF15/19 | Colorectal | [118] |
| Endometrial | [119] | |
| Hepatocellular carcinoma | [120] | |
| Prostate | [121] | |
| iFGFs | Colorectal | [122] |
| Prostate | [123,124] | |
| Triple negative breast cancer | [125] |
FGF, fibroblast growth factor; iFGFs, intracellular FGFs.