Table 2.
Examples of cancer subtypes for which Fibroblast Growth Factor Receptor (FGFR) genetic aberrations have been identified.
| FGFR Gene | Cancer Subtype | Associated References |
|---|---|---|
| FGFR1 | Breast cancer | [10,176,177] |
| Colorectal cancer | [178,179] | |
| Gastrointestinal | [180] | |
| Glioma | [181,182] | |
| Head and neck | [183] | |
| Non-small cell lung cancer | [184,185,186,187,188] | |
| Ovarian cancer | [189] | |
| Pancreatic ductal adenocarcinoma | [190] | |
| Prostate cancer | [191,192,193,194] | |
| Small cell lung cancer | [186,195,196,197] | |
| Urothelial cancer | [189] | |
| FGFR2 | Breast cancer | [10,198] |
| Cholangiocarcinoma | [199,200,201] | |
| Endometrial cancer | [202] | |
| Gastric cancer | [9,203,204] | |
| Non-small cell lung cancer | [205] | |
| FGFR3 | Bladder cancer | [189,206,207,208,209,210,211,212,213,214] |
| Cervical cancer | [209,215,216] | |
| Glioma | [181,189] | |
| Non-small cell lung cancer | [189,205,217,218] | |
| FGFR4 | Adrenocortical cancers | [219] |
| Breast cancer | [189] |