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Sequences and binding co-ordinates of recommended positive control exon skipping AOs designed for the human SMN and mouse Smn transcripts.
| Species | Coordinates | Sequence 5′-3′ |
|---|---|---|
| Human | SMN H7A(+ 07 + 31) SMN H7A(+ 13 + 32) |
ACC UUC CUU CUU UUU GAU UUU GUC U CAC CUU CCU UCU UUU UGA UU |
| Mouse | Smn M7A(+ 07 + 31) Smn M5A(+ 12 + 36) |
ACU UUC CUU CUU UUU UAU UUU GUC U AGG CGG CGG CGG CGG GCC GUU GAA U |
