From 29th February 2020 to 30th June 2020, 124 patients confirmed positive for SARS-Cov-2 infection were admitted to the ICU. At ICU admission, all patients presented intubated and mechanically ventilated. Thirty-eight patients died before receiving respiratory physiotherapy (RPT), while eighty-six patients started RPT when deemed ready. Data concerning gas exchange during RPT were available for 66 patients, while data concerning lung ultrasound (LUS) imaging during RPT were available for 20 patients, of whom 14 presented a concomitant computed tomography (CT) scan performed within a few days from the RPT session.