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Duration of response per patient assessed by IRC. a The patient was assessed by independent reviewers as having equivocal progressive disease on day 39 prior to attaining a partial response according to RANO criteria at day 249, which permit a partial response after progressive disease that is not unequivocal. The last dose of radiotherapy was given 5.4 months prior to the first dose of bintrafusp alfa. IRC, independent review committee; PD, progressive disease; PR, partial response.
