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. 2021 May 14;13(10):2376. doi: 10.3390/cancers13102376

Figure 1.

Figure 1

G9a mRNA and protein expression levels are prognostic markers of patients with hepatocellular carcinoma (HCC). (A) Box and whisker plot demonstrating a comparison of G9a expression levels between HCC and normal tissues which were downloaded from The Cancer Genome Atlas HCC dataset via UCSC Xena. This dataset shows the gene-level transcription estimates, as in log2(x + 1) transformed RSEM (reads per expectation maximization) normalized count. Unpaired two-tailed Student’s t-test was used for statistical analysis. (B) Kaplan–Meier plot of overall and disease-free survival of HCC patients stratified by G9a mRNA expression levels. A log-rank test was used to show differences between groups. (C) Representative photos of G9a immunohistochemical staining in HCC tissues with scores of 0–3. A negative control was also shown in which HCC tissues were incubated with normal mouse IgG replacing the anti-G9a monoclonal antibody. Scale bars, 50 μm. (D) Kaplan–Meier plot of overall and disease-free survival of HCC patients stratified by G9a protein expression levels. A log-rank test was used to show differences between groups.