Table 2.
Univariate and multivariate analyses of potential prognostic variables.
| Parameter | Comparison | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|
| HR (95% CI) | p-Value | HR (95% CI) | p-Value | ||
| G9a score | low (≥240); high (<240) | 1.52 (1.01–2.27) | 0.0442 * | 1.45 (0.96–2.20) | 0.0805 |
| AJCC stage | I or II; III or IV | 1.71 (1.11–2.63) | 0.0148 * | 1.50 (0.83–2.72) | 0.184 |
| Sex | male; female | 0.87 (0.49–1.55) | 0.6314 | 1.10 (0.59–2.05) | 0.7714 |
| AFP level (ng/mL) | ≥500; <500 | 1.56 (0.97–2.51) | 0.0662 | 1.45 (0.85–2.49) | 0.1762 |
| Tumor size (cm) | ≥5; <5 | 1.48 (0.99–2.20) | 0.0546 | 1.12 (0.64–1.97) | 0.6843 |
| Portal vein involvement | yes; no | 1.74 (1.15–2.63) | 0.0096 * | 1.81 (1.13–2.90) | 0.0147 * |
| Microvessel invasion | yes; no | 0.88 (0.59–1.33) | 0.5579 | 0.64 (0.40–1.03) | 0.0659 |
| HBV | positive; negative | 1.29 (0.86–1.95) | 0.2237 | 1.32 (0.82–2.15) | 0.2589 |
| HCV | positive; negative | 0.89 (0.57–1.41) | 0.6348 | 1.15 (0.67–1.97) | 0.6102 |
HR, hazard ratio; CI, confidence interval; AFP, α-fetoprotein; HBV, hepatitis B virus; HCV, hepatitis C virus. * p < 0.05.