Figure 4.

Proposed diagnostic flow chart for screening FD in men and in women with LVH. IVST = interventricular septal thickness; PWT = posterior wall thickness. * Potential red flags that should raise the clinical suspicion and prompt screening of FD in LVH patients include: Teochew people, heart failure, and arrhythmias; the presence of hypertension and/or aortic/mitral valve pathology should not exclude patients from FD screening. †Plasma lysoGb3 is a potential primary screening biomarker for FD in females.