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. Author manuscript; available in PMC: 2021 May 27.
Published in final edited form as: J Gastroenterol. 2020 Jan 13;55(5):523–532. doi: 10.1007/s00535-020-01663-1

Fig. 4.

Fig. 4

Individual persistent changes of alkaline phosphatase throughout disease course (Each line represents single patient. First and last dot represent SAP at diagnosis and last SAP value, respectively. Any dots in-between these points represent a persistent SAP group change where the individual had 2 or more SAP values measured at least 3 months apart). a Individuals who had normal SAP at the time of diagnosis; b individuals who had SAP of 1–1.49 × ULN at the time of diagnosis; c individuals who had SAP ≥ 1.5 × ULN at the time of diagnosis. Note axes broken in scales change for clarity at 5 × ULN for y-axis and at 20 years for x-axis