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. Author manuscript; available in PMC: 2021 May 27.
Published in final edited form as: J Hepatol. 2020 Sep 17;74(2):394–406. doi: 10.1016/j.jhep.2020.09.010

Fig. 6. Comparative SUMOylated protein profile between PHCs and NHCs in culture after SUMOl-immunoprecipitation.

Fig. 6.

(A) Representative immunoblot of SUMO-IP in NHC and PHC. (B) Volcano plot of all identified SUMOl-IP proteins (n = 67) by mass spectrometry comparing fold enrichment in PHCs to NHCs. Proteomic analyses of significant identified proteins (n = 26) in aforementioned groups by (C) gene ontology and (D) PPI network. Line color in PPI network indicates type of interaction evidence. IP, immunoprecipitation; NHCs, normal human cholangiocytes; PHCs, polycystic human cholangiocytes; PPI, protein-protein interaction.