Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Probability of target attainment (PTA) achievement in the groups of CrCl 101–130 mL/min (a), 80–100 mL/min (b), 51–19 mL/min (c), 30–50 mL/min (d), 11–29 mL/min (e), 1–10 mL/min (f). The detail of PTA results is found in Supplementary material Tables S1–S6. LD: loading dose (in mg colistin base activity), MD: maintenance dose (in colistin base activity), US-FDA: Food and Drug Administration of United State, EMA: European Medicines Agency, q12: every 12 h.
