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. 2021 May 20;22(1):542. doi: 10.3892/ol.2021.12803

Table I.

Measurement of tumor growth. (a) × width (b) in mm; volume was calculated as (axb2)/2 in mm3.

Group ID# Day 7 Day 9 Day 11 Day 13 Day 15 Day 17 Day 19
Control 790 Measurement, axb mm 7.32×6.41 7.75×6.70 8.48×6.93 9.60×8.18 11.02×8.47 12.70×9.38 13.48×10.81
Volume, mm3 150.38 173.95 203.63 321.18 395.29 558.70 787.61
564 Measurement, axb mm 7.38×6.18 7.52×6.80 8.19×7.02 9.61×9.61 10.92×10.88 11.97×10.92 12.57×12.06
Volume, mm3 140.93 173.95 201.80 443.75 646.32 713.69 913.69
609 Measurement, axb mm 5.74×4.42 6.28×5.26 6.93×5.67 7.84×7.47 9.46×8.57 10.52×9.75 11.47×10.38
Volume, mm3 56.07 86.88 111.40 218.74 347.39 500.03 617.83
566 Measurement, axb mm 5.58×4.47 6.14×5.04 6.87×5.53 8.74×6.47 12.28×8.25 13.27×9.06 14.47×10.69
Volume, mm3 55.75 77.98 105.05 182.93 417.90 544.62 826.90
565 Measurement, axb mm 4.91×3.66 5.08×4.01 5.57×4.71 6.60×4.56 8.99×6.02 9.37×7.98 10.53×8.75
Volume, mm3 32.89 40.84 61.78 68.62 162.90 298.48 402.72
R53 661 Measurement, axb mm 7.21×5.73 7.8×6.45 8.21×6.86 9.53×9.21 11.62×10.98 12.01×10.88 13.41×12.17
Volume, mm3 118.51 162.19 193.22 404.20 699.93 711.35 992.81
611 Measurement, axb mm 6.92×5.65 7.65×6.16 8.58×7.17 9.32×8.58 10.91×8.94 11.56×9.38 12.82×10.23
Volume, mm3 110.36 145.05 220.47 342.68 435.82 508.84 670.53
638 Measurement, axb mm 5.67×4.65 6.12×5.15 7.89×6.94 8.63×7.86 9.33×8.09 10.64×9.50 11.14×10.02
Volume, mm3 61.21 81.23 189.76 266.63 305.06 480.37 559.74
791 Measurement, axb mm 5.12×3.92 5.67×5.06 6.77×6.38 7.41×6.94 9.21×8.66 11.02×9.70 11.98×11.25
Volume, mm3 39.24 72.49 137.91 178.35 345.64 518.30 757.56
792 Measurement, axb mm 4.24×3.86 4.98×3.67 5.83×4.58 5.59×3.89 6.71×4.92 9.21×7.78 8.87×7.34
Volume, mm3 31.60 33.52 61.24 42.38 81.13 278.94 239.25
CAR-T 947 Measurement, axb mm 7.32×5.64 6.20×4.58 4.90×3.38 7.63×5.75 9.35×6.83 9.62×8.12 11.51×8.86
Volume, mm3 116.42 65.03 27.99 126.05 218.08 317.40 451.46
568 Measurement, axb mm 7.17×4.59 6.70×3.98 6.58×3.43 8.34×6.56 9.96×8.02 10.28×9.43 10.95×10.23
Volume, mm3 75.53 52.94 38.71 179.62 320.33 456.99 612.79
610 Measurement, axb mm 6.23×4.63 5.31×3.98 3.74×3.31 3.87×3.67 5.89×5.13 6.35×5.45 7.03×6.32
Volume, mm3 66.65 41.99 20.44 26.00 77.43 94.24 140.36
563 Measurement, axb mm 5.45×4.59 4.13×3.84 3.66×3.30 4.23×1.66 4.89×2.95 5.20×4.00 6.79×5.30
Volume, mm3 57.42 30.45 19.97 5.82 21.30 41.56 95.22
578 Measurement, axb mm 4.07×3.66 2.57×2.07 1.00×1.00 0.00×0.00 0.00×0.00 2.91×2.75 4.96×4.92
Volume, mm3 27.26 5.51 0.50 0.00 0.00 11.00 60.00
CAR-T+R53 960 Measurement, axb mm 7.02×5.50 6.42×5.10 7.55×6.14 7.63×6.60 7.88×7.32 7.56×7.08 8.56×7.16
Volume, mm3 106.18 83.49 142.24 165.94 211.11 189.65 219.65
794 Measurement, axb mm 6.78×5.46 5.98×5.02 6.53×5.49 6.87×5.80 7.38×6.28 6.72×5.73 7.58×6.19
Volume, mm3 101.00 75.30 98.50 115.40 145.70 110.30 145.20
585 Measurement, axb mm 6.55×5.20 5.43×4.77 7.08×5.78 7.47×5.69 7.24×5.79 6.82×5.20 7.28×5.34
Volume, mm3 88.56 61.77 118.41 120.81 121.51 92.21 103.76
665 Measurement, axb mm 6.21×5.18 5.34×4.39 6.10×4.02 6.53×3.55 6.98×4.49 6.54×4.79 6.74×5.03
Volume, mm3 83.20 51.50 49.30 41.20 70.30 75.10 85.20
636 Measurement, axb mm 6.50×5.01 6.23×3.80 5.03×3.07 4.18×2.28 4.42×2.74 6.19×3.88 6.36×3.86
Volume, mm3 81.58 44.98 23.64 10.89 16.61 46.49 47.44

Volume was calculated as (axb2)/2. a, length; b, width; CAR, chimeric antigen receptor. ID#, ear ring tagging number of mice.