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. 2021 May 26;23:61. doi: 10.1186/s13058-021-01437-4

Fig. 1.

Fig. 1

Changes of the tumor immune microenvironment induced by neoadjuvant chemotherapy. a, b Changes from biopsy (pre-neoadjuvant) to surgical tissue sample (post-neoadjuvant) for each patient, in all cases (left), in the no-pCR (middle), and in the pCR groups (right), for tumor-infiltrating lymphocytes (TILs) and TIM-3, respectively. c, d Comparison of changes from pre-neoadjuvant to post-neoadjuvant (as % change) between the no-pCR and the pCR groups, for TILs and LAG-3, respectively