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. 2021 May 18;10(10):2175. doi: 10.3390/jcm10102175

Figure 3.

Figure 3

A typical overdosing of a 12-year-old patient using Propofol children model (Paedfusor) in TCI mode. You can observe a depression in the alfa band in the middle of the spectrogram display (Time is from up to down). This depression is considered a sign of overdosing and requires the reduction of the concentration of propofol observed at the down point of the screen (BIS bilateral monitor left, Ezfusor™ infusion system right). The adequate doses are only 2.2 ug/ml in this case.