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. 2021 May 26;21:616. doi: 10.1186/s12885-021-08308-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Expression levels of the 17 central genes in lung adenocarcinoma patients compared to healthy people. The GEPIA website was applied to validate the expression level of the 17 central genes between LAC patients and normal people. All 17 genes were lowly expressed in LAC specimens compared to normal specimens (*P < 0.05). Red indicates LAC tissues (n = 483) and gray indicates normal tissues (n = 347)