Table 1.
Baseline characteristics of participants according to quartiles of changes in TyG index from 2006 to 2010
| Characteristics | Overall | Quartiles of changes in TyG index | P value | |||
|---|---|---|---|---|---|---|
| Q1 (< − 0.31) | Q2 (− 0.31 to 0.05) | Q3 (0.05–0.41) | Q4 (≥ 0.41) | |||
| No. of participants | 62,443 | 15,610 | 15,611 | 15,611 | 15,611 | |
| Age, years | 49.07 ± 11.84 | 47.35 ± 11.77 | 48.82 ± 11.98 | 49.96 ± 11.95 | 50.15 ± 11.46 | < 0.0001 |
| Men, n (%) | 47,827 (76.59) | 12,059 (77.25) | 11,562 (74.06) | 11,806 (75.63) | 12,400 (79.44) | < 0.0001 |
| High school or above, n (%) | 13,614 (22.56) | 3755 (25.09) | 3649 (24.17) | 3322 (21.98) | 2888 (19.02) | < 0.0001 |
| Income > 800 RMB/month, n (%) | 8878 (14.72) | 2385 (15.95) | 2410 (15.98) | 2090 (13.84) | 1993 (13.14) | < 0.0001 |
| Body mass index, kg/m2 | 25.03 ± 3.46 | 24.84 ± 3.44 | 24.86 ± 3.47 | 25.01 ± 3.46 | 25.40 ± 3.46 | < 0.0001 |
| Systolic blood pressure, mmHg | 128.36 ± 19.81 | 126.14 ± 19.20 | 126.98 ± 19.40 | 128.71 ± 19.95 | 131.60 ± 20.24 | < 0.0001 |
| Diastolic blood pressure, mmHg | 82.63 ± 11.41 | 81.42 ± 11.23 | 81.86 ± 11.16 | 82.78 ± 11.35 | 84.44 ± 11.65 | < 0.0001 |
| Current smoker, n (%) | 20,552 (33.81) | 5082 (33.28) | 4739 (31.10) | 4975 (32.67) | 5756 (38.25) | < 0.0001 |
| Current alcohol use, n (%) | 23,413 (38.51) | 5665 (37.06) | 5429 (35.62) | 5816 (38.19) | 6503 (43.22) | < 0.0001 |
| Active physical activity, n (%) | 55,080 (91.46) | 13,387 (89.74) | 13,850 (91.92) | 13,922 (92.31) | 13,921 (91.85) | < 0.0001 |
| Hypertension, n (%) | 6035 (9.66) | 1416 (9.07) | 1485 (9.51) | 1470 (9.42) | 1664 (10.66) | < 0.0001 |
| Diabetes mellitus, n (%) | 1489 (2.38) | 339 (2.17) | 288 (1.85) | 337 (2.16) | 525 (3.36) | < 0.0001 |
| Dyslipidemia, n (%) | 3183 (5.10) | 737 (4.72) | 833 (5.34) | 770 (4.93) | 843 (5.40) | 0.0166 |
| Antihypertensive agents, n (%) | 5185 (8.30) | 1209 (7.75) | 1273 (8.16) | 1282 (8.21) | 1421 (9.10) | 0.0002 |
| Antidiabetic agents, n (%) | 1144 (1.83) | 269 (1.72) | 222 (1.42) | 252 (1.61) | 401 (2.57) | < 0.0001 |
| Lipid-lowering agents, n (%) | 465 (0.74) | 102 (0.65) | 134 (0.86) | 108 (0.69) | 121 (0.77) | 0.1526 |
| Total cholesterol, mmol/L | 4.91 ± 1.13 | 4.90 ± 1.04 | 4.94 ± 1.02 | 4.97 ± 1.02 | 4.84 ± 1.40 | < 0.0001 |
| HDL cholesterol, mmol/L | 1.56 ± 0.39 | 1.58 ± 0.40 | 1.56 ± 0.39 | 1.55 ± 0.39 | 1.53 ± 0.40 | < 0.0001 |
| LDL cholesterol, mmol/L | 2.29 ± 0.89 | 2.25 ± 0.94 | 2.28 ± 0.86 | 2.31 ± 0.87 | 2.32 ± 0.89 | < 0.0001 |
| Hs-CRP, mg/dL | 2.29 ± 6.37 | 2.14 ± 4.96 | 2.21 ± 5.37 | 2.23 ± 6.94 | 2.60 ± 7.79 | < 0.0001 |
LDL low-density lipoprotein, HDL high-density lipoprotein, hs-CRP high-sensitivity C-reactive protein, TyG triglyceride glucose