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. Author manuscript; available in PMC: 2021 May 27.
Published in final edited form as: J Cell Physiol. 2013 Sep;228(9):1819–1826. doi: 10.1002/jcp.24333

Fig. 3.

Fig. 3.

A–C: In 3-week-old mice, Myocd+/− mice showed left-shift and significantly elevated pEC50 values as an evidence of bladder hypersensitivity to cholinergic agents (A). α-glycyrrhetinic acid (GA), a gap junction inhibitor did not affect bladder sensitivity of WT mice (B) but reversed these changes in Myocd+/− mice (C). D–F: In 15-week-old mice, Myocd+/− mice also showed left-shift and significantly elevated pEC50 values as an evidence of hypersensitivity to cholinergic agents (D). α-GA did not affect bladder sensitivity of WT mice (E) but reversed these changes in Myocd+/− mice (F). *Statistically significant difference (P < 0.05).