TABLE 2.
Clinical and Endoscopic Characteristics at Diagnosis of Patients with UC by Severity Group
| Overall UC (n = 601) | Mild UC (n = 78) | Moderate UC (n = 273) | Severe UC (n = 250) | P | |
|---|---|---|---|---|---|
| Gender (%) | 0.52 | ||||
| Male | 283 (47) | 41 (53) | 129 (47) | 113 (45) | |
| Female | 318 (53) | 37 (47) | 144 (53) | 137 (55) | |
| Age at diagnosis, median (range), yr | 27 (2–73) | 28 (9–66) | 26 (6–60) | 27 (2–73) | 0.17 |
| Age group (%) | 0.08 | ||||
| ≤16 | 80 (13) | 10 (13) | 33 (12) | 37 (15) | |
| 17–40 | 417 (70) | 54 (69) | 204 (75) | 159 (64) | |
| >40 | 104 (17) | 14 (18) | 36 (13) | 54 (22) | |
| Ethnicity (%) | 0.60 | ||||
| White | 507 (84) | 68 (87) | 231 (85) | 208 (83) | |
| Asian | 61 (10) | 6 (8) | 24 (9) | 31 (12) | |
| Black | 7 (1) | 2 (3) | 4 (1) | 1 (0) | |
| Hispanic | 2 (0) | 0 | 1 (0) | 1 (0) | |
| Others | 24 (5) | 2 (2) | 13 (5) | 9 (5) | |
| Family history—IBD (%) | 0.35 | ||||
| 1st degree | 120 (20) | 22 (28) | 49 (18) | 49 (20) | |
| 2nd degree or more | 92 (15) | 9 (12) | 45 (16) | 38 (15) | |
| None | 389 (65) | 47 (60) | 179 (66) | 163 (65) | |
| Extent at diagnosis (%) | 0.001 | ||||
| E1 | 89 (14) | 17 (22) | 44 (16) | 28 (11) | |
| E2 | 178 (30) | 33 (42) | 79 (29) | 66 (26) | |
| E3 | 142 (24) | 10 (13) | 56 (21) | 76 (31) | |
| Unknown | 191 (32) | 18 (23) | 93 (34) | 80 (32) | |
| Smoking at diagnosis (%) | 0.12 | ||||
| Yes | 83 (14) | 10 (13) | 47 (17) | 26 (11) | |
| Ex-smoker | 135 (22) | 13 (17) | 62 (23) | 60 (26) | |
| No | 357 (60) | 54 (69) | 154 (56) | 149 (63) | |
| Unknown | 26 (4) | 1 (1) | 10 (4) | 15 (6) | |
| Appendectomy before diagnosis (%) | 12 (2) | 2 (3) | 5 (2) | 5 (2) | 0.96 |
E1, proctitis; E2, colitis up to the splenic flexure; E3, colitis proximal to the splenic flexure.