. Author manuscript; available in PMC: 2021 May 27.

Published in final edited form as: Inflamm Bowel Dis. 2015 Sep;21(9):2097–2105. doi: 10.1097/MIB.0000000000000466

TABLE 4.

Clinical Parameters at Diagnosis Associated with Severe UC

	Moderate + Mild UC (n = 351)	Severe UC (n = 250)	OR (95% CI)	p
Age (%), yr				0.02
>40	50 (14)	54 (22)	1.66 (1.08–2.54)
≤40	301 (86)	196 (78)
Extent at diagnosis (%)				0.0003
E3	66 (19)	76 (30)	2.12 (1.40–3.21)
E1/E2	173 (49)	94 (38)
Unknown	112 (32)	80 (32)
Smoking (%)				0.06
Yes	57 (16)	26 (10)	0.62 (0.38–1.02)
Ex-smoker/no	283 (81)	209 (84)
Unknown	11 (3)	15 (6)
Ethnicity (%)				0.12
Asian	30 (9)	31 (12)	1.52 (0.90–2.59)
Others	321 (91)	219 (88)
Appendectomy before diagnosis (%)	7 (2)	5 (2)		0.96

CI, confidence interval; E1, proctitis; E2, colitis up to the splenic flexure; E3, colitis proximal to the splenic flexure.