Figure 10.

Fluorescence microscopic z-scans of untreated TR146 cells (A,D) and TR146 cells treated with 400 ng/mL IL-1ß (B,E) and 300 ng/mL TNF-α (C,F). Particle uptake was performed with 500 µg/mL (A–C) and 750 µg/mL (D–F) NLC. Cell nuclei were stained with Hoechst (blue) and the cytoskeleton was stained with Alexa Fluor 488 Phalloidin (green). The circles represent particle uptake/internalization into TR146 cells. NLC were labeled with oil red o (red).