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. 2021 May 18;10(5):1114. doi: 10.3390/foods10051114

Figure 2.

Figure 2

Decreasing viability of HepaRG cells 24 h after PA exposure. Cell viability was measured by the MTT assay. The mean values out of three biological replicates with three technical replicates each were normalized to the solvent control (SC, 2.5% ACN, 1.7% DMSO). Triton X-100 (0.05%) was used as positive control (PC). The heat map shows the cell viabilities in percent of the solvent control. Blue color indicates a decrease in cell viability and yellow indicates an increase. Statistics: * p < 0.05, ** p < 0.01, *** p < 0.001 (one-way ANOVA followed by Dunnett‘s post hoc test versus the solvent control). Mean values, standard deviations and p-values can be found in the supplemental material. Abbreviations for structural characteristics of the PAs: retronecine (R), heliotrine (H), otonecine (O) or platynecine (P) type; free base (B), monoester (M), open-chained diester (D(o)) or cyclic diester (D(c)).