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. 2021 May 18;11(5):428. doi: 10.3390/jpm11050428

Table 3.

Cox regression analyses of one-year mortality.

Univariate Multivariate
HR 95% CI p-Value HR 95% CI p-Value
PNI 0.85 0.81–0.89 <001 0.87 0.81–0.94 <001
Age (years) 1.00 0.97–1.02 0.916
Sex (male) 1.00 0.97–1.02 0.916
BMI 0.89 0.81–0.97 0.011 0.96 0.87–1.06 0.422
DM 1.19 0.43–3.28 0.738
HTN 0.70 0.22–2.22 0.547
MELD scores 1.19 0.98–1.45 0.088 0.94 0.74–1.20 0.635
CTP scores 2.45 1.70–3.52 <001 0.97 0.49–1.94 0.936
TNM staging <001 <001
1 1.00 (Ref.) 1.00 (Ref.)
2 2.35 0.52–10.65 0.270 2.36 0.52–10.79 0.270
3 3.92 1.23–12.55 0.022 3.67 1.14–11.81 0.030
4A 10.37 5.13–20.96 <001 8.85 4.29–18.22 <001
4B 19.14 7.58–48.30 <001 9.26 3.42–25.11 <001
Operation time (min) 1.00 1.00–1.00 0.028 1.00 1.00–1.00 0.713
Total fluids (mL/kg) 1.02 1.00–1.03 <001 1.00 0.99–1.02 0.548
Synthetic colloid use 0.88 0.51–1.54 0.662
Urine output (mL/kg/h) 1.07 0.87–1.31 0.515
RBC transfusion 1.29 1.19–1.41 <001 1.03 0.44–2.43 0.948

HR: hazard ratio; CI: confidence interval; PNI: prognostic nutritional index; BMI: body mass index; DM: diabetes mellitus; HTN: hypertension; MELD; model for end-stage liver disease; CTP: Child–Turcotte–Pugh; RBC: red blood cell. Values are expressed as mean ± standard deviation, median (interquartile range), or n (proportion).