Table 3.

Genes known for their reproductive biology function, in the vicinity of significant SNPs.

SNP	Gene	BTA	Location of SNP	p-Value	Function	Overall SNP Effect
BovineHD1100009366	LHCGR	11	31339285	7.8 × 10−6	Steroid Synthesis	0.057
BovineHD1100009366	FSHR	11	31339285	7.8 × 10−6	Steroid Synthesis	0.057
BovineHD4100003128	LEP	4	92253894	4.0 × 10−6	GnRH Secretion	0.053
BovineHD1400007251	MOS	14	23304037	1.8 × 10−7	Oocyte Maturation	0.059
BovineHD2200014848	CDC25A	22	51689566	4.6 × 10−6	Oocyte Maturation	−0.050
BovineHD2200003516	AVCR2B	22	11918372	4.6 × 10−7	TGF-β Signaling	−0.056
BovineHD2200000211	EGFR	22	878627	8.0 × 10−6	GnRH Signaling	−0.052
BovineHD2500007459	MAPK3	25	26160282	3.4 × 10−6	GnRH Signaling	0.060
BovineHD1000021917	ESR2	10	76586616	3.0 × 10−10	Estrogen Signaling	−0.114
BovineHD0900023775	GRM1	9	83806867	9.5 × 10−10	Glutamate Signaling	−0.066
BovineHD1700011908	GRIA2	17	41973761	3.0 × 10−6	Glutamate Synapse	0.098
BovineHD2500002242	GRIN2A	25	8381736	4.2 × 10−6	Glutamate Synapse	0.057
BovineHD2200005404	GRM7	22	18702200	4.4 × 10−6	Glutamate Synapse	0.070
BovineHD0600018549	GABRA4	6	65504186	3.1 × 10−6	GABAergic Synapse	−0.050
BovineHD0200007364	GAD1	2	25614206	7.9 × 10−6	GABAergic Synapse	−0.053
BovineHD0600018549	GABRB1	6	65504186	3.1 × 10−6	GABAergic Synapse	−0.050
BovineHD0600018311	GABRA2	6	64738586	3.3 × 10−6	GABAergic Synapse	−0.048
BovineHD0600018311	GABRG1	6	64738586	3.3 × 10−6	GABAergic Synapse	−0.048
BovineHD1300000677	PLCB4	13	2565300	9.7 × 10−6	Calcium Signaling	0.047
BovineHD2200006328	ITPR1	22	21699681	5.2 × 10−10	Calcium Signaling	−0.092
BovineHD0400018696	CREB5	4	67587933	3.8 × 10−6	cAMP Signaling	−0.082
BovineHD1800005855	ADCY7	18	18675150	4.5 × 10−7	cAMP Signaling	0.059
BovineHD0600018878	CNGA1	6	66763069	7.2 × 10−7	cAMP Signaling	0.062
BovineHD0700033604	PDE4A	7	15081779	2.2 × 10−7	cAMP Signaling	0.064
BovineHD0300002075	HSD17B7	3	6617455	1.3 × 10−6	Steroid Synthesis	−0.052
BovineHD2100009894	CYP11A	21	34099081	4.2 × 10−7	Steroid Synthesis	−0.052
BovineHD1400007252	PLAG1	14	23313248	1.8 × 10−7	Transcription Regulation	0.059
BovineHD2300013198	TFAP2A	23	45590544	1.7 × 10−6	Transcription Regulation	0.058
BovineHD1100029888	TTF1	11	102587601	3.2 × 10−6	Transcription Regulation	0.046
BovineHD2100008703	CHRNA7	21	29677844	1.9 × 10−7	Cholinergic Synapse	−0.063
BovineHD2700004441	MTNR1A	27	16259785	1.1 × 10−6	Melatonin Receptor	−0.048