Table II.

Performance of Truenat MTB-RIF (Truenat Version 1.5) in comparison with comprehensive laboratory reference standards for detection of RIF resistance

Candidate test	Comprehensive laboratory reference standard
		R	S	Total
					Sensitivity	0.76 (0.69, 0.82)
Truenat	R	138	44	182	Specificity	0.95 (0.93, 0.96)
	S	43	788	831	Positive predictive value	0.76 (0.69, 0.82)
	Total	181	832	1013	Negative predictive value	0.95 (0.93, 0.96)
					Positive likelihood ratio	14.42 (10.69, 19.44)
					Negative likelihood ratio	0.25 (0.19, 0.33)

Truenat in comparison with the cumulative gold standard yielded a sensitivity, specificity, positive predictive value, negative predictive value are 76.2, 94.7, 75.8 and 94.7 per cent, respectively for detection of RIF resistance. R, resistant; S, susceptible