Table IV.
Detection of RIF resistance by Truenat (Trunat Version 2.0) in comparison with gold standards
| MGIT | Xpert | LPA | Truenat | Total | |
|---|---|---|---|---|---|
| Resistant (R) (%) | Susceptible (S) (%) | ||||
| R | R | R | 28 (87.5) | 4 (12.5) | 32 |
| R | R | S | 5 (100) | 0 (0) | 5 |
| R | S | R | 0 (0) | 2 (100) | 2 |
| R | S | S | 0 (0) | 21 (100) | 21 |
| S | R | R | 11 (73.3) | 4 (26.7) | 15 |
| S | R | S | 4 (80) | 1 (20) | 5 |
| S | S | R | 0 | 0 | 0 |
| S | S | S | 3 (0.5) | 550 (99.5) | 553 |
| Total | 51 (8.1) | 582 (91.9) | 633 | ||
Truenat MTB/RIF assay in comparison with the comprehensive laboratory reference standards (rows 1 and 8) yielded a sensitivity and specificity of 87.5 and 99.5 per cent, respectively for detection of RIF resistance. MGIT, mycobacteria growth indicator tube; LPA, line probe assay