Fig. 5.

INX-1 inhibits ectopic activation of the DVB motor neuron. (A and C) Representative traces showing change of GCaMP3 fluorescence at the AVL/DVB NMJs during the defecation cycle in adult animals of the indicated genotypes expressing GCaMP3 under the unc-47(mini) promoter. (B and D, Left) Histograms showing the time when each calcium spike occurred after pBoc in wild-type and inx-1 mutants. (Right) Average frequency of calcium spikes per cycle grouped by normal and ectopic spikes in wild-type and inx-1 mutants. Means and SEs are shown. Asterisks indicate significant differences: ***P < 0.001 in Student’s t test.