Table 1. HR performance in testing set.

Sample-weight-corrected hazard ratios are estimated for PHS166 and PHS46 in the testing set, using age-of-onset of any or clinically significant prostate cancer. The percent change for each metric is calculated using the value of PHS46 as the reference. Mean values and 95% confidence intervals are reported.

Type of cancer	HR	PHS46	PHS166	Change (%)
Any	HR95/50	3.29 [2.73,3.77]	4.45 [3.68,5.06]	36 [18,53]
	HR80/20	5.15 [3.92,6.18]	7.85 [6.04,9.33]	53 [25,78]
	HR20/50	0.44 [0.40,0.49]	0.37 [0.33,0.40]	−18 [−25,−10]
Clinically Significant	HR95/50	3.72 [2.89,4.43]	5.09 [3.84,6.05]	37 [13,59]
	HR80/20	6.12 [4.18,7.67]	9.45 [6.17,11.79]	55 [17,88]
	HR20/50	0.41 [0.35,0.47]	0.34 [0.29,0.39]	−18 [−28,−9]