Table 2.
Predictions and assays for T cell recognition in drug-induced A*02 ligands
|
HLA ligand |
Predicted binding affinity for HLA-A*02 [nM] |
T cell recognition score |
ELISpot result |
| ALLESSLRQA | 414.5 | −0.260 | negative |
| ALTSVVVTL | 35.8 | −0.018 | negative |
| FVDDYTVRV | 6.8 | 0.130 | negative |
| GLATDVQTV | 23.5 | 0.037 | negative |
| IIDDNHAIV | 115.8 | 0.160 | positive |
| KVLERVNAV | 19.4 | 0.200 | negative |
| RLAEAHAKV | 16.2 | 0.089 | negative |
| SLDTQPKKV | 1878.4 | −0.380 | negative |