Skip to main content
. 2021 May 21;15:1061–1073. doi: 10.2147/PPA.S311836

Table 3.

Attribute-Level Preference Weights: Total and by Latent Class Group

Total (n=200) Side Effects (n=69) Quick Onset (n=47) Quick Onset and Long Duration (n=84)
Attribute Level Μ (95% CI) Μ (95% CI) Μ (95% CI) Μ (95% CI)
Speed of onset - “Medication takes effect in __” 4 hours −3.32 (−3.55–3.09) −1.86 (−2.11–1.60) −4.65 (−5.05–4.26) −3.78 (−4.04–3.52)
2 hours 0.17 (0.10–0.23) −0.03 (−0.13–0.06) 0.16 (−0.01–0.33) 0.34 (0.25–0.43)
1.5 hours 1.25 (1.18–1.32) 0.91 (0.80–1.02) 1.51 (1.37–1.64) 1.38 (1.29–1.47)
1 hour 1.90 (1.73–2.08) 0.98 (0.75–1.21) 2.99 (2.65–3.32) 2.06 (1.85–2.26)
Duration of effect - “Medication lasts for __ after it is taken” 8 hours −1.28 (−1.48–1.07) −0.62 (−0.88–0.35) −0.15 (−0.52–0.22) −2.45 (−2.66–2.24)
12 hours 0.21 (0.15–0.27) 0.34 (0.24–0.45) 0.04 (−0.09–0.17) 0.20 (0.11–0.28)
14 hours 0.64 (0.56–0.72) 0.33 (0.21–0.44) 0.50 (0.33–0.66) 0.98 (0.88–1.08)
16 hours 0.42 (0.27–0.58) −0.05 (−0.26–0.16) −0.39 (−0.68–0.10) 1.27 (1.10–1.44)
Insomnia/sleep disturbance - “__ risk of insomnia or disruptions to sleep” 31% −1.27 (−1.37–1.16) −1.64 (−1.80–1.47) −0.54 (−0.70–0.38) −1.37 (−1.52–1.23)
18% −0.07 (−0.13–0.02) −0.16 (−0.27–0.06) 0.06 (−0.07–0.18) −0.07 (−0.15–0.00)
5% 1.34 (1.23–1.46) 1.80 (1.63–1.97) 0.48 (0.31–0.66) 1.45 (1.30–1.60)
Headache - “__ risk of headache” 32% −1.89 (−2.02–1.75) −2.66 (−2.86–2.46) −1.01 (−1.20–0.83) −1.74 (−1.90–1.58)
15% 0.32 (0.26–0.38) 0.29 (0.19–0.38) 0.16 (0.04–0.27) 0.44 (0.35–0.52)
<1% 1.57 (1.42–1.71) 2.37 (2.17–2.57) 0.86 (0.66–1.06) 1.30 (1.12–1.48)
Nervousness/anxiety/irritability - “__ risk of feeling nervous, anxious, or irritable” 13% −0.91 (−1.01–0.80) −1.24 (−1.39–1.09) −0.37 (−0.60–0.14) −0.93 (−1.07–0.79)
7% 0.14 (0.09–0.20) 0.21 (0.10–0.32) 0.15 (0.03–0.27) 0.08 (0.01–0.16)
<1% 0.77 (0.66–0.87) 1.04 (0.86–1.21) 0.22 (0.01–0.43) 0.85 (0.71–0.99)
Rebound - “__ risk of rebound/crash effect when medication effect wears off (making you feel eg, moody, tired, drained, or sluggish)” 9% −0.62 (−0.74–0.50) −0.50 (−0.69–0.30) 0.01 (−0.20–0.22) −1.08 (−1.23–0.93)
3% −0.04 (−0.12–0.05) −0.46 (−0.56–0.35) 0.05 (−0.13–0.24) 0.26 (0.14–0.38)
<1% 0.66 (0.56–0.76) 0.96 (0.79–1.12) −0.06 (−0.24–0.12) 0.82 (0.70–0.94)

Note: Text appearing in quotations shows the text seen by respondents for each attribute.

Abbreviations: CI, confidence interval; M, mean.