Table 2:

Diagnostic parameters for both readers (R1, R2) and reading approaches (NC-MRI, DCE-MRI)

	Sensitivity (TP/TP+FN)	95% CI	Specificity (TN/TN+FN)	95% CI	LR+	95% CI	LR−	95% CI
CE-MRI (R1)	94.0 (64/67)	85.4 – 98.3	80.4 (45/56)	67.6 – 89.8	4.79	2.8 – 8.2	0.074	0.03 – 0.2
CE-MRI (R2)	94.0 (63/67)	85.4 – 98.3	76.8 (43/56)	63.6 – 87.0	4.05	2.5 – 6.5	0.078	0.03 – 0.2
NC-MRI (R1)	91.0 (61/67)	81.5 – 96.6	75.0 (42/56)	61.6 – 85.6	3.64	2.3 – 5.8	0.12	0.05 – 0.3
NC-MRI (R2)	91.0 (61/67)	81.5 – 96.6	71.4 (40/56)	57.8 – 82.7	3.19	2.1 – 4.9	0.13	0.06 – 0.3

NC-MRI: Non-contrast MRI (readout-segmented DWI), CE-MRI: Contrast-enhanced MRI (DCE-MRI plus T2w), TP: true positives, TN: true negatives, FP: false positives, FN: false negatives, CI: confidence interval, LR+: positive likelihood ratio, LR-: negative likelihood ratio, R1: reader one, R2: reader two