Table 3.
Antibody signals to ganglio-series glycolipids in pre-transplant NHPs
| IgM signal |
IgG signal |
||||||
|---|---|---|---|---|---|---|---|
| a411 print # | Abbreviation | Description | Biological relevance | Median | SD | Median | SD |
| 124 | GA2di - 37 | GalNAcb1–4Galb - BSA | possible [40] | 15.89 | 0.47 | 12.23 | 1.99 |
| 170 | GA2di - 28 | GalNAcb1–4Galb - BSA | possible [40] | 15.87 | 0.50 | 11.97 | 2.02 |
| 22 | GA1di - 11 | Galb1–3GalNAcb – HSA | possible [41] | 14.63 | 0.34 | 10.88 | 0.91 |
| 116 | GA2di - 05 | GalNAcb1–4Galb - BSA | possible [40] | 14.19 | 0.97 | 11.37 | 1.69 |
| 312 | GM2-Sp - 07 | Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [32] | 14.09 | 1.65 | 10.18 | 1.32 |
| 301 | GD3-Sp - 08 | Neu5Aca2–8Neu5Aca2–3Galb1–4Glcb-Sp-BSA | strong [32] | 14.07 | 1.84 | 10.09 | 1.44 |
| 96 | GM2-Sp - 14 | Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [32] | 13.61 | 1.65 | 9.40 | 0.99 |
| 271 | GD3-Sp - 04 | Neu5Aca2–8Neu5Aca2–3Galb1–4Glcb-Sp-BSA | strong [32] | 13.36 | 1.21 | 9.02 | 0.86 |
| 57 | GA1 – 20 | Galb1–3GalNAcb1–4Galb1-BSA | possible [41] | 13.35 | 1.01 | 10.33 | 1.14 |
| 118 | GA1 – 06 | Galb1–3GalNAcb1–4Galb1-BSA | possible [41] | 13.21 | 0.77 | 9.11 | 1.00 |
| 282 | GM3-Sp - 11 | Neu5Aca2–3Galb1–4Glcb-Sp-BSA | strong [32] | 12.65 | 0.51 | 9.02 | 0.96 |
| 288 | GT2-Sp - 08 | Neu5Aca2–8Neu5Aca2–8Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [36] | 12.47 | 1.05 | 9.01 | 1.48 |
| 82 | GM1a - 29 | Galb1–3GalNAcb1–4(Neu5Aca2–3)Galb1–4(Glc)HSA | strong [32] | 12.24 | 1.01 | 9.05 | 0.57 |
| 336 | GM2-Sp - 04 | Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [32] | 12.14 | 1.59 | 8.37 | 1.03 |
| 46 | GM3 – 12 | Neu5Aca2–3Galb1–4Glc-APD-HSA | strong [32] | 12.12 | 2.13 | 8.91 | 1.37 |
| 330 | GD2-Sp - 10 | Neu5Aca2–8Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | possible [37, 42] | 12.09 | 1.70 | 10.26 | 1.69 |
| 250 | GM3(Gc)-Sp - 14 | Neu5Gca2–3Galb1–4Glcb-Sp-BSA | possible [32, 42] | 12.03 | 2.08 | 7.92 | 0.76 |
| 325 | GT3-Sp - 07 | Neu5Aca2–8Neu5Aca2–8Neu5Aca2–3Galb1–4Glcb-Sp-BSA | possible [42] | 11.57 | 1.51 | 8.12 | 0.69 |
| 236 | GD1a-Sp - 10 | Neu5Aca2–3[Neu5Aca2–3Galb1–3GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [38] | 11.37 | 1.55 | 7.88 | 1.14 |
| 314 | GD2-Sp - 04 | Neu5Aca2–8Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | possible [37, 42] | 11.33 | 2.24 | 9.65 | 1.68 |
| 285 | GM3-Sp - 04 | Neu5Aca2–3Galb1–4Glcb-Sp-BSA | strong [32] | 11.17 | 1.13 | 8.15 | 0.84 |
| 257 | GT3-Sp - 03 | Neu5Aca2–8Neu5Aca2–8Neu5Aca2–3Galb1–4Glcb-Sp-BSA | possible [42] | 11.10 | 1.99 | 7.58 | 0.81 |
| 295 | GT2-Sp - 03 | Neu5Aca2–8Neu5Aca2–8Neu5Aca2–3[GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [36] | 11.10 | 1.18 | 8.25 | 1.52 |
| 229 | GD1a-Sp - 05 | Neu5Aca2–3[Neu5Aca2–3Galb1–3GalNAcb1–4]Galb1–4Glcb-Sp-BSA | strong [32] | 10.44 | 2.03 | 7.26 | 0.92 |
| 322 | GM3(Gc)-Sp - 05 | Neu5Gca2–3Galb1–4Glcb-Sp-BSA | possible [32, 42] | 9.78 | 1.04 | 7.23 | 0.21 |
| 318 | GD1b - 05 | Neu5Aca2–8Siaa2–3(Galb1–3GalNAcb1–4)Galb1–4-BSA | possible [37] | 8.27 | 1.41 | 7.80 | 0.88 |
Biological relevance is stated high when it is reported that the antigen is expressed on wild type or gene modified porcine cells/tissues. Biological relevance is stated possible when it is reported that the antigen is expressed on mammalian cells/tissues. Numbers in brackets show reference. NA data not available, NHP nonhuman primate