Table 2.
List of differentially expressed proteins in the comparison of the intracellular proteome of S. aureus N315 with either the deletion of the SprG1/SprF1 TA system (ΔΔ) or with the (over)expression of the SprF1 antitoxin (ΔΔSprF1).
| No. | Protein (Acronym) | Accession Number | N315-ΔΔ vs. N315 | N315-ΔΔSprF1 vs. N315 | N315-ΔΔSprF1 vs. N315-ΔΔ |
|---|---|---|---|---|---|
| Logarithmic phase | |||||
| 1 | Coenzyme A disulfide reductase (Cdr) | Q7A6H1 | 1.68 ↓ * | ||
| 2 | Immunoglobulin-binding protein (Sbi) | Q99RL2 | 1.72 ↑ | ||
| 3 | 50S ribosomal protein L1 (RplA) | Q99W68 | 1.82 ↑ | ||
| 4 | 50S ribosomal protein L2 (RplB) | P60432 | 1.51 ↓ | ||
| 5 | Uncharacterized protein (SA1737) | Q7A4P4 | 1.50 ↓ | ||
| 6 | Uracil phosphoribosyltransferase (Upp) | P67396 | 2.19 ↑ | ||
| Stationary phase | |||||
| 1 | Pyruvate dehydrogenase E1 component subunit β (PdhB) | P99063 | 2.19 ↓ | 1.82 ↓ | |
| 2 | Succinate--CoA ligase (ADP-forming) subunit α (SucD) | P99070 | 1.55 ↓ | ||
| 3 | Putative peptidyl-prolyl cis-trans isomerase (PpiB) | Q7A6I1 | 2.19 ↓ | 1.82 ↓ | |
| 4 | 3-hydroxyacyl-(acyl-carrier-protein) dehydrataseFabZ (FabZ) | P64108 | 2.36 ↓ | ||
| 5 | 6,7-dimethyl-8-ribityllumazine synthase (RibH) | P99141 | 1.58 ↓ | 2.36 ↓ | |
| 6 | Alanine dehydrogenase 2 (Ald2) | Q99TF4 | 1.86 ↓ | ||
| 7 | Phenylalanine--tRNA ligase α subunit (PheS) | P68848 | 1.55 ↓ | ||
| 8 | ATP-dependent 6-phosphofructokinase (PfkA) | P99165 | 1.55 ↓ | ||
| 9 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (GpmI) | P64270 | 1.53 ↑ | ||
| 10 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (OdhB) | Q7A5N4 | 1.53 ↑ | ||
| 11 | Catalase (KatA) | Q7A5T2 | 1.66 ↑ | 1.90 ↑ | |
| 12 | Cell division protein FtsA (FtsA) | P63765 | 1.53 ↑ | ||
| 13 | ATP-dependent Clp protease ATP-binding subunit ClpL (ClpL) | Q7A3F4 | 1.53 ↑ | ||
| 14 | Fructose-bisphosphate aldolase class 1 (Fda) | P99117 | 1.54 ↓ | ||
| 15 | Riboflavin biosynthesis protein RibBA (RibBA) | Q7A511 | 1.62 ↓ | ||
| 16 | Glyceraldehyde-3-phosphate dehydrogenase 1 (GapA1) | P99136 | 1.62 ↓ | ||
* the arrow denotes the direction of regulation; ↑ up- and ↓ down-regulation in comparison to the second component from the pair, respectively.