Table 1.

List of the five variants of the spike protein RBD which have the broadest in vitro neutralizing spectrum, as measured in [17]. Their measured average resistance to six nAbs compared to the wild-type are given, as well as their fitness ${\varphi }^{\mathrm{nAb}}$ predicted on the basis of the 31 nAbs from the ${\mathcal{D}}^{\mathrm{nAb}}$ set.

Variants	Resistance to nAbs	${\mathit{\varphi }}^{\mathbf{nAb}}$
S349A	35%	1.1
G446A	37%	1.4
G447A	41%	1.6
N448A	26%	1.5
E484A	44%	1.1