Table 1.
Demographic and serum biomarker information of the participants with no NAFLD in baseline in the Kailuan cohort study.
| Demographic Characteristics | Total (n=16,839) | Female (n=5,418) | Male (n=11,421) | P-value | |
|---|---|---|---|---|---|
| Age, years, mean ± SD | 50.62 ± 12.95 | 48.57 ± 11.82 | 51.60 ± 13.34 | <0.01 | |
| BMI, kg/m2, mean ± SD | 23.79 ± 2.94 | 23.43 ± 3.07 | 23.97 ± 2.86 | <0.01 | |
| Obesity, BMI≥28kg/m2 | 1,277 (7.58) | 382 (7.05) | 895 (7.84) | 0.07 | |
| Non-obesity, BMI<28kg/m2 | 15,562 (92.42) | 5,036 (92.95) | 10,526 (92.16) | ||
| Smoking, n (%) | Never or ever | 12,203 (72.47) | 5,365 (99.02) | 6,838 (59.87) | <0.01 |
| Current | 4,636 (27.53) | 53 (0.98) | 4,583 (40.13) | ||
| Marital Status, n (%) | Married | 16,196 (96.18) | 5,224 (96.42) | 10,972 (96.07) | 0.27 |
| Divorced, single or widowed | 643 (3.82) | 194 (3.58) | 449 (3.93) | ||
| Work Type, n (%) | Mental | 2,705 (16.06) | 1,490 (27.50) | 1,215 (10.64) | <0.01 |
| Physical | 14,134 (83.94) | 3,928 (72.50) | 10,206 (89.36) | ||
| Education Level, n (%) | Below high school | 11,567 (68.69) | 3,232 (59.65) | 8,335 (72.98) | <0.01 |
| High school or above | 5,272 (31.31) | 2,186 (40.35) | 3,086 (27.02) | ||
| Physical Activity, n (%) | No | 5,129 (30.46) | 1,538 (28.39) | 3,591 (31.44) | <0.01 |
| Yes | 11,710 (69.54) | 3,880 (71.61) | 7,830 (68.56) | ||
| SUA, µmol/L, median (IQR) | 263.00 (214.00, 318.00) | 228.00 (193.10, 272.00) | 281.00 (229.00, 338.00) | <0.01 | |
| SBP, mmHg, mean ± SD | 125.96 ± 18.83 | 120.63 ± 19.13 | 128.49 ± 18.14 | <0.01 | |
| DBP, mmHg, mean ± SD | 81.62 ± 10.35 | 78.24 ± 10.24 | 83.23 ± 10.01 | <0.01 | |
| TG, mmol/L, median (IQR) | 1.11 (0.82, 1.51) | 1.05 (0.76, 1.41) | 1.15 (0.85, 1.56) | <0.01 | |
| TC, mmol/L, median (IQR) | 4.72 (4.17, 5.28) | 4.70 (4.15, 5.38) | 4.73 (4.18, 5.23) | 0.56 | |
| FBG, mmol/L, median (IQR) | 5.18 (4.80, 5.62) | 5.03 (4.69, 5.48) | 5.20 (4.86, 5.70) | <0.01 | |
| CRP, mg/L, median (IQR) | 0.90 (0.40, 2.01) | 0.83 (0.40, 1.83) | 0.90 (0.31, 2.14) | 0.46 | |
| Cr, µmol/L, median (IQR) | 78.50 (66.00, 94.52) | 66.00 (56.00, 79.00) | 84.00 (72.60, 99.10) | <0.01 | |
| Incident NAFLD, n (%) | No | 11,735 (69.69) | 3,901 (72.00) | 7,834 (68.59) | <0.01 |
| Yes | 5,104 (30.31) | 1,517 (28.00) | 3,587 (31.41) | ||
BMI, Body Mass Index; Cr, Creatinine; CRP, C-reactive Protein; FBG, Fasting Blood Glucose; IQR, interquartile range; NAFLD, Nonalcoholic Fatty Liver Disease; SBP, Systolic Blood Pressure; SD, Standard Deviation; SUA, Serum Uric Acid; TC, Total Cholesterol; TG, Triglyceride.