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. 2021 May 27;13(1):e12204. doi: 10.1002/dad2.12204

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© 2021 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Plasma 217+tau assay has wide dynamic range and good dilution linearity. A, A 12‐point calibrant curve was run on the plasma p217+tau assay on five separate days, revealing consistent signal with a wide dynamic range (5–30,000 fg/mL). B, A panel of Alzheimer's disease (AD) serum and plasma samples (n = 4) were measured in the plasma p217+tau assay at dilutions of 1:2, 1:3, 1:4, 1:5, and 1:6. Dilution corrected concentrations were compared to 1:3 dilution, revealing all dilutions tested were within 20% of each other