Table 1.
Baseline characteristics of patients with normal P-wave, partial interatrial block or advanced interatrial block.
| Normal P-wave (n = 119) |
PIAB (n = 524) |
AIAB (n = 72) |
p* | p** | |
|---|---|---|---|---|---|
| Age, years | 64 (55, 70) | 64 (57, 71) | 70 (62, 77) | .849 | <.001 |
| Sex, female | 29 (24.4) | 86 (16.4) | 25 (34.7) | .094 | .276 |
| CHA2DS2-VASc | 1 (0, 3) | 2 (1, 3) | 2 (1, 4) | .219 | <.001 |
| CHA2DS2-VASc >1 | 59 (49.2) | 288 (54.0) | 51 (69.9) | .726 | .014 |
| Heart failure | 13 (10.9) | 97 (18.5) | 10 (13.9) | .116 | .999 |
| Hypertension | 49 (41.2) | 274 (52.3) | 42 (58.3) | .066 | .050 |
| eGFR <60 ml/mina | 7 (12.1) | 33 (13.1) | 10 (28.6) | .999 | .112 |
| Diabetes | 16 (13.4) | 76 (14.5) | 13 (18.1) | .999 | .822 |
| Prior stroke or TIA | 6 (5.0) | 32 (6.1) | 10 (13.9) | .999 | .112 |
| Vascular disease | 12 (10.1) | 90 (17.2) | 20 (27.8) | .140 | .004 |
| First AF episode | 70 (58.8) | 357 (68.1) | 52 (72.2) | .134 | .130 |
| AF episode over 30 daysa | 43 (66.2) | 175 (72.3) | 30 (75.0) | .714 | .776 |
| AF history over 180 daysb | 45 (44.6) | 173 (40.0) | 20 (37.0) | .864 | .794 |
| Prior CVc | 35 (31.5) | 110 (21.9) | 12 (17.6) | .072 | .108 |
| Left atrial diameter, mmd | 44.5 (40, 48) | 47 (42, 50) | 44.5 (38, 47) | .041 | .800 |
| Mild enlargement | 33 (68.8) | 130 (82.3) | 7 (58.3) | .132 | .999 |
| Moderate enlargement | 16 (33.3) | 71 (44.9) | 4 (33.3) | .366 | .999 |
| Medication at CVe | |||||
| Verapamil | 3 (2.6) | 8 (1.5) | 1 (1.4) | .866 | .999 |
| Digoxin | 26 (22.2) | 133 (25.5) | 18 (25.0) | .999 | .999 |
| B-Blocker | 97 (82.9) | 423 (80.7) | 59 (81.9) | .999 | .999 |
| Any antiarrhythmic | 8 (6.8) | 18 (3.5) | 2 (2.8) | .234 | .646 |
| Medication at dischargef | |||||
| Verapamil | 0 (0) | 4 (0.8) | 0 (0) | .999 | |
| Digoxin | 8 (6.8) | 39 (7.5) | 9 (12.5) | .999 | .400 |
| B-Blocker | 91 (77.8) | 424 (81.1) | 61 (84.7) | .878 | .528 |
| Any antiarrhythmic | 11 (9.4) | 28 (5.4) | 2 (2.8) | .264 | .272 |
| ECG parameters | |||||
| Heart rate, bpm | 61 (53, 71) | 61 (54, 70) | 61 (54, 73) | .965 | .902 |
| PR-interval, ms | 166 (154, 182) | 195 (176, 216) | 206 (184, 220) | <.001 | <.001 |
| Atrioventricular block | 13 (10.9) | 212 (40.5) | 42 (58.3) | <.001 | <.001 |
| P-wave duration, ms | 110 (105, 115) | 135 (130, 145) | 150 (140, 170) | ||
| Ventricular conduction issue | 20 (16.8) | 124 (23.7) | 14 (19.4) | .228 | .999 |
| Left ventricular hypertrophy | 11 (9.6) | 64 (12.7) | 12 (17.4) | .858 | .332 |
Data are given as median (interquartile range) for continuous variables and as frequency (percentage) for categorical variables.
*PIAB compared to normal P-wave; **AIAB compared to normal P-wave.
Data is missing in a370, b127, c33, d497, e465, f<10.
AF: atrial fibrillation; AIAB: advanced interatrial block; CHA2DS2-VASc: congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, and prior stroke, transient ischaemic attack or thromboembolism (doubled), vascular disease, age 65 to 74, sex category (female); CV: cardioversion; ECG: electrocardiogram; eGFR: estimated glomerular filtration rate; PIAB: partial interatrial block; TIA: transient ischaemic attack.