Table 1.
Baseline characteristics of study participants.
| Characteristic | Non-obese (n=26) | Obese (n=25) | p-value | |
|---|---|---|---|---|
| Samples | Gastroscopy (%) | 12 (46) | 12 (48) | |
| Colonoscopy (%) | 13 (50) | 10 (40) | ||
| Blood (%) | 21 (81) | 24 (96) | ||
| Bariatric surgery (%) | 0 (0) | 6 (24) | ||
| Age (years) | 54.6 ± 3.2 | 50.8 ± 3.4 | 0.42 | |
| Sex | ||||
| Male (%) | Male (%) | 13 (50) | 13 (52) | 1.00 |
| Female (%) | 13 (50) | 12 (48) | ||
| Ethnicity | Caucasian (%) | 23 (88) | 23 (92) | 1.00 |
| Other (black, asian, hispanic) (%) | 3 (12) | 2 (8) | ||
| Body weight parameters | BMI (kg/m2) | 23.4 ± 0.7 | 38.8 ± 1.2 | <0.001 |
| Weight (kg) | 69.2 ± 2.3 | 119.3 ± 6.1 | <0.001 | |
| Waist circumference (cm) | 90.3 ± 2.4 | 126.6 ± 3.4 | <0.001 | |
| WHR | 0.96 ± 0.01 | 1.01 ± 0.02 | 0.01 | |
| WHtR | 0.54 ± 0.01 | 0.72 ± 0.02 | <0.001 | |
| cvRF | Diabetes mellitus (%) | 0 (0) | 5 (20) | 0.02 |
| Hypertension (%) | 8 (31) | 14 (56) | 0.09 | |
| Dyslipidemia (%) | 9 (35) | 8 (32) | 1.00 | |
| Positive family history (%) | 3 (12) | 2 (8) | 1.00 | |
| Laboratory parameters | CRP (mg/l) | 1.6 ± 0.3 | 6.3 ± 1.2 | <0.001 |
| ASAT (U/l) | 23.6 ± 2.2 | 24.5 ± 1.3 | 0.43 | |
| ALAT (U/l) | 26.2 ± 2.8 | 37.3 ± 3.5 | 0.02 | |
| Cholesterol (mmol/l) | 4.7 ± 0.2 | 4.8 ± 0.2 | 0.80 | |
| Triglycerides (mmol/l) | 1.2 ± 0.2 | 1.6 ± 0.2 | 0.02 | |
| LDL (mmol/l) | 2.6 ± 0.2 | 2.8 ± 0.2 | 0.43 | |
| HDL (mmol/l) | 1.6 ± 0.1 | 1.3 ± 0.1 | 0.01 |
Data were expressed as mean ± standard error of the mean (SEM) and number (%). WHR was calculated waist circumference divided by hip circumference, and WHtR was calculated waist circumference divided by height. BMI, Body mass index; WHR, Waist-to-Hip Ratio; WHtR, Waist-to-Height Ratio; cvRF, cardiovascular risk factors; CRP, C-reactive protein; ASAT, Aspartate Aminotransferase; ALAT, Alanine Aminotransferase; LDL, Low-density lipoprotein; HDL, High-density lipoprotein.