Table 4.
Overview of the main studies dealing with the pesticides exposures of military personnel.
Pollutant | Sample Size | Time after Exposure | Solider Nationality | Exposure Site (Operation Theater) | Environmental Monitoring (Exposure) | Biomarkers (Early Biological Effect) | Biomarker Description | Early Clinical Effect | Late Clinical Effect | References |
---|---|---|---|---|---|---|---|---|---|---|
Pesticides | 187 | Day 0, 14, and 28 of the wearing period, and 28 days after termination | Germany | Germany | Permethrin concentration in uniforms: 1300 mg/m2 |
Exposure biomarker in urines | Permethrin metabolites: cis-3-(2,2-dichlorovinyl)-2,2-dimethyl-(1-cyclopropane) carboxylic acid (cis-DCCA), trans-3-(2,2-dichlorovinyl)-2,2-dimethyl-(1-cyclopropane) carboxylic acid (trans-DCCA), and 3-phenoxybenzoic acid (3-PBA) | - | - | [55,56] |
549 (Study I); 195 (Study II) | Before wearing uniforms, after 14 days, after 28 days of wearing, and 28 days after cessation of wearing uniform | Germany | Two sub-cohorts in Germany and one in Afghanistan | Permethrin concentration in uniforms: 0.13 mg/cm2 | Exposure biomarker in urines | Permethrin metabolites: cis-DCCA, trans-DCCA 3-PBA | - | - | [57] | |
224 | - | United States | Iraq/Afghanistan | - | - | - | - | Chronic multisymptom illness. | [58] |