TABLE 2:

Averaged ADC and FA values for the control subjects and patients

A: ADC values, mm2/sec
ROI	Control Subjects, × 10−6	Patients, ×10−6	P Value
Internal capsule	674 ± 81	683 ± 59	.732
Splenium*	769 ± 61	628 ± 74	.001
Thalamus	718 ± 60	719 ± 62	.975
Putamen	677 ± 75	707 ± 55	.184

B: FA values
ROI	Control Subjects	Patients	P Value
Internal capsule*	0.725 ± 0.066	0.624 ± 0.072	<.001
Splenium*	0.808 ± 0.060	0.678 ± 0.010	.002
Thalamus	0.377 ± 0.075	0.401 ± 0.040	.147
Putamen	0.286 ± 0.081	0.307 ± 0.040	.257

Note.—Table lists the mean ADC and FA values ± SD for all patients and control subjects within the respective ROIs. Left- and right-sided ADC and FA values were averaged. A statistically significant ADC decrease is seen for the splenium, and a statistically significant FA decrease is seen for the internal capsule. A P value of <.005 was considered to indicate a statistically significant difference. Analysis was performed by using a two-tailed Wilcoxon rank sum test.

^*Statistically significant difference.