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. 2021 May 13;9:672739. doi: 10.3389/fchem.2021.672739

Table 1.

Noble metal nanomaterials and their application to virus biosensors.

Core noble metal nanomaterials Techniques Target virus Analyte Limit of detection References
AuNPs Electrochemical (DPV) SARS-CoV-2 Nucleic acids (RNA) 200 copies/mL Zhao et al., 2021
Electrochemical (DPV) SARS-CoV-2 Protein 7.8 × 10−1 pg/mL Mahari et al., 2020
Electrochemical (SWV) MERS-CoV Protein 0.4 pg/mL Layqah and Eissa, 2019
Optical (Fluorescence) Influenza virus Protein 1.7 × 10−2 pg/mL Nasrin et al., 2020
Optical (SERS) Influenza virus Protein 6.7 × 103 pg/mL Maneeprakorn et al., 2016
AgNPs Electrochemical (LSV) Influenza virus Protein 1.6 pg/mL Huang et al., 2016
Optical (Colorimetry) MERS-CoV Nucleic acids (DNA) 1.53 nM Teengam et al., 2017
Optical (SERS) SARS-CoV Protein 1 pg/mL Liu et al., 2021
PtNPs Electrochemical (DPV) Influenza virus Protein 7.6 × 10−1 pg/mL Yang et al., 2016
Optical (Colorimetry) Influenza virus Protein 2.5 × 10−2 HAU/mL Matsumura et al., 2018