Fig 4.

Patient 3. Early fungal abscess due to Aspergillus infection.

A, On Gd-enhanced T1-weighted imaging, the lesion has a thin rim of peripheral enhancement.

B, On FLAIR imaging, the lesion has heterogeneous signal intensity with minimal surrounding edema.

C and D, DWI (C) and ADC (D) maps show peripherally decreased diffusion, with elevated diffusion in the center of the lesion.

E, Hematoxylin-eosin stain (100×) shows acute and chronic inflammation in the brain parenchyma, without a well-defined capsule.

F, Methenamine silver stain (250×) shows septate and 45°-branching hyphae in necrotic parenchyma.