Table 2. Functional capacity, physical activity level, and quality of life (mean values±SD) at baseline and after 12 weeks in both groups using a mixed linear model and physical activity level assessed by the IPAQ, using a non-parametric two-way analysis of variance for repeated measures.
| Home-based n=11 | Centre-based n=12 | p-value Group×Time | p-value Group | p-value Time | |||
|---|---|---|---|---|---|---|---|
| Baseline | 12 weeks | Baseline | 12 weeks | ||||
| Cardiopulmonary test | |||||||
| Exercise time (s) | 579±144 | 645±119 | 567±148 | 645±90 | 0.872 | 0.842 | 0.059 |
| Peak heart rate (bpm) | 117±13 | 122±18 | 116±22 | 123±26 | 0.848 | 0.985 | 0.268 |
| Peak VO2 (mL/kg/min) | 19.2±3.9 | 20.0±4.2 | 19.5±5.3 | 23.2±6.1 | 0.085 | 0.448 | 0.011* |
| AT VO2 (mL/kg/min) | 13.3±2.7 | 13.5±3.7 | 12.9±2.9 | 14.5±3.7 | 0.367 | 0.920 | 0.235 |
| VE/VCO2 slope | 31.6±6.4 | 33.4±5.8 | 31.4±8.0 | 30.7±8.1 | 0.196 | 0.594 | 0.657 |
| Maximal ventilation (L/min) | 51.4±15.2 | 62.9±28.2 | 58.8±30.6 | 74.4±33.7 | 0.775 | 0.429 | 0.015** |
| Oxygen pulse | 12.1±2.7 | 12.1±3.1 | 13.6±3.9 | 15.2±4.0 | 0.108 | 0.129 | 0.130 |
| Peak respiratory exchange ratio | 1.1±0.1 | 1.1±0.1 | 1.1±0.2 | 1.1±0.1 | 0.868 | 0.852 | 0.781 |
| 6MW distance | 460.7±63.7 | 500.7±86.1 | 513.1±77.1 | 538.6±72.3 | 0.805 | 0.013 | 0.002£ |
| Daily physical activity | |||||||
| IPAQ | |||||||
| Sedentary, n (%) | 1 (10) | 0 (0) | 5 (42) | 0 (10) | 0.299 | 0.428 | 0.001 |
| Irregularly active, n (%) | 5 (45) | 1 (10) | 3 (25) | 0 (10) | |||
| Active, n (%) | 5 (45) | 10 (90) | 4 (33) | 12 (100) | |||
| Accelerometry | |||||||
| Number of steps per day | 7335±015 | 6873±2819 | 5640±2259 | 6541±2225 | 0.001α,β | 0.258 | 0.832 |
| Number of sedentary bouts per day | 18.5±8.5 | 17.1±6.7 | 23.9±5.8 | 22.4±6.9 | 0.972 | 0.062 | 0.214 |
| Sedentary bouts length (mins/bout) | 19.7±10.0 | 18.1±7.8 | 26.3±7.3 | 23.0±7.7 | 0.472 | 0.092 | 0.050 |
| Sedentary time (mins/day) | 539±133 | 526±111 | 625±86 | 587±140 | 0.581 | 0.113 | 0.266 |
| Time spent on light activities (mins/day) | 360±118 | 333±104 | 299±87 | 323±90 | 0.080 | 0.382 | 0.931 |
| Time spent on moderate-vigorous activities (mins/day) | 23±16 | 23±9 | 13±9 | 21±16 | 0.199 | 0.218 | 0.190 |
| Health-related quality of life | |||||||
| MLHF | 29±33 | 28±33 | 35±24 | 22±13 | 0.039# | 0.965 | 0.023 |
| SF-36 - Mental Health | 73±32 | 68±33 | 61±23 | 72±16 | 0.001## | 0.848 | 0.342 |
AT, anaerobic threshold; IPAQ, International Physical Activity Questionnaire; MLHF, Minnesota Living with Heart Failure Questionnaire; SF-36, Short-Form 36 questionnaire; VCO2, volume of exhaled carbon dioxide; VE, expiratory minute volume; VO2, oxygen uptake; 6 MW, 6-min walk test. *Mean difference=2.2 (95% CI: 0.5-3.9); **Mean difference=12.9 (95% CI: 2.6-23.2); £ Mean difference=32.4 (95% CI: 16.5-48.4); αHome-based vs centre-based at baseline: p=0.001, Mean difference=2103 (95% CI: 1229-2977); βCentre-based at baseline vs 12 weeks: p=0.031, Mean difference=901 (95% CI: 67-1735); #Centre-based at baseline vs 12 weeks: p=0.014, Mean difference=13.2 (95% CI: 2.3-24.1); ##p=0.031 Home-based vs centre-based at baseline and p=0.037 Centre-based at baseline vs 12 weeks, using Tukey multiple comparison procedure.