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Comparison of AC and CEX for rAAV2/8, rAAV2/2, rAAV2/2.GL, and rAAV2/2.NN. Chromatography with AC (A) and CEX (B). Purple depicts the flow through and, thus, loss of rAAVs during the loading process onto the column (flowthrough), light green shows the yield of rAAV in the elution, and pink illustrates the loss of rAAVs during the cleaning in place (CIP) process. Minimum, n = 3 (except for AC rAAV2/2, n = 2)). rAAV, recombinant adeno-associated virus.
