Table 2. Assessment of AmST-MC and AmT-MC Stability under Various Storing Conditions.
| AUL Ø (μm) |
PDI |
# MCs (1012 MCs/mL) |
stability indexa |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| entry | pressure (mbar) | temperature (°C) | time | AmST | AmT | AmST | AmT | AmST | AmT | AmST | AmT |
| 1 | ∼1000 | 23 | 1 h | 1.44 | 1.28 | 0.5 | 0.5 | 6.97 | 6.64 | 1.00 | 1.00 |
| 2 | ∼1000 | 23 | 1 d | 1.44 | 1.28 | 0.5 | 0.5 | 6.97 | 6.64 | 1.00 | 1.00 |
| 3 | ∼1000 | 23 | 180 d | 1.50 | 1.30 | 0.5 | 0.5 | 6.83 | 6.52 | 0.99 | 0.98 |
| 4 | 2026 | 121 | 30 m | 1.50 | 1.30 | 0.5 | 0.5 | 6.90 | 6.52 | 0.99 | 0.98 |
| 5 | ∼1000 | –20 | 7 d | 1.76 | 1.72 | 0.5 | 0.3 | 2.51 | 3.25 | 0.36 | 0.49 |
a
Determined as the ratio between the number of capsules before and after exposure to specified conditions.