Table 4. Stability of Representative Carbamates and the Reference Oseltamivir in Porcine Liver Homogenate in the Absence and in the Presence of the Carboxylesterase 1 Inhibitor BNPP (1 mM) and Inhibition of Degradation of These Compounds.

	stability (%)a
comp.	in the absence of BNNP	in the presence of BNNP	inhibition of degradation (%)b
14	76 ± 2	87 ± 9	46
27	62 ± 5	79 ± 9	45
33	59 ± 6	81 ± 8	54
46	56 ± 8	76 ± 5	45
oseltamivir	11 ± 2	97 ± 1	97

^aPercent of parent remaining after incubation in porcine liver homogenate for 30 min; values are means ± standard deviations, n = 3.

^bCalculated from the mean values of the stability data.