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. 2021 Mar 30;15(5):8130–8141. doi: 10.1021/acsnano.0c09893

Figure 5.

Figure 5

Normalized response (NR) of the sensors with (a and c) PEDOT:PSS and (b and d) p(g0T2-g6T2) channels. In a and b, the recorded response was to a single Aβ aggregate or peptide concentration (221 nM) as a function of VG and the devices were gated with Ag/AgCl or Au. In c) and d), the gate electrode was Ag/AgCl. For the microfluidic-free device, a 1 mm thick PDMS well was placed on top of the OECT to confine 100 μL of PBS over an area with a diameter of 1 cm. NR was calculated at VG = 0.6 V for PEDOT:PSS and VG = −0.1 V for p(g0T2-g6T2) devices. Error bars represent the SD from at least three different channels. VD was −0.6 V in all measurements. Panels e and f show the normalized change in impedance magnitude measured at 10 kHz for PEDOT:PSS and p(g0T2-g6T2) films, respectively.