Table 1. (A) The search strategy. (B) A summary of the variables extracted from included papers.

A) Search strategy
#1	Search (Meningitis, Cryptococcal[Mesh] OR cryptococcal meningitis)
#2	Search (trial[mesh] OR Clinical Trial OR Clinical Trial, Phase I OR Clinical Trial, Phase II OR Clinical Trial, Phase III OR Clinical Trial, Phase IV OR Randomized Controlled Trial)
#3	Search (Prospective Studies[Mesh] or prospective)
	Searching #1 and #2 and #3 up to and including 04 March 2020
B) Variables extracted from included papers
Study		• Year of publication • Period of study • Location of study • Type of healthcare facility • Study design • Intervention(s)	• Control • Inclusion criteria • Exclusion criteria • Primary outcome • Secondary outcome(s)
Screening and Randomisation		• Number screened • Number screen failures • Reasons for each	• Withdrawals • Loss to follow-up
Participants		• Number of participants • Gender • Antiretroviral status	• Baseline Glasgow Coma Scale • First episode or relapse
Researchers		• Number of authors • Gender • Country of origin	• Country of residence during research period
Funders		• Name of funders • Category of funder	• Location of funder • Funding amount