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. 2021 May 13;12:659736. doi: 10.3389/fmicb.2021.659736

TABLE 5.

List of approved events containing Vip3A proteins in commercial Bt cotton in different countries.

S. No. Event Developer Name of Countries and approval year Countries No. Trade Name Genes Target traits
1. COT102 (IR102) Syngenta Australia (2005), Canada (2011), China (2015), Colombia (2016), Costa Rica (2017), Japan (2012), Mexico (2010), New Zealand (2005), Philippines (2015), South Korea (2014), Taiwan (2015), United States (2005) 12 VIPCOTTM Cotton vip3A(a) Lepidopteran insect resistance
2. GHB614 × T304-40 × GHB119 × COT102 Bayer Crop Science Australia (2016), Brazil (2017), Japan, Mexico (2015), Philippines (2020), South Korea (2015), Taiwan (2016) 7 Twin Link Plus (GlytolTM × TwinlinkTM × VIPCOTTM Cotton) cry1Ab + cry2Ae + vip3A(a) + mepsps Herbicide tolerance and lepidopteran insect resistance
3. COT102 × COT67B Syngenta Costa Rica (2009) 1 VIPCOTTM Cotton cry1Ab + vip3A(a) Insect resistance
4. COT102 × COT67B × MON88913 Syngenta and Monsanto Costa Rica (2009) 1 VIPCOTTM Roundup Ready FlexTM Cotton cry1Ab + vip3A(a) + cp4 epsps Herbicide tolerance and Insect resistance
5. 3006-210-23 × 281-24-236 × MON88913 × COT102 Dow AgroSciences LLC Japan (2013), Mexico (2014), South Korea (2014) 3 Wide Strike 3 (WidestrikeTM × Roundup Ready FlexTM × VIPCOTTM Cotton) cry1Ac + vip3A(a) + cry1F + cp4 epsps + pat Herbicide tolerance and lepidopteran insect resistance
6. COT102 × MON15985 Monsanto Australia, Japan, Mexico (2014) 3 Bollgard® III cry1Ac + cry2Ab2 + vip3A(a) Lepidopteran insect resistance
7. COT102 × MON15985 × MON88913 Monsanto Australia (2014), Brazil (2016), Japan (2014), South Korea (2015), Taiwan (2016) 5 Bollgard® III × Roundup ReadyTM FlexTM cry1Ac + cry2Ab2 + vip3A(a) + cp4 epsps Herbicide tolerance and lepidopteran insect resistance
8. COT102 × MON15985 × MON88913 × MON88701 Monsa nto Australia (2016), Brazil (2018), Colombia (2012), Japan (2016), Mexico (2015), South Korea (2016), Taiwan (2017) 7 Not available cry1Ac + cry2Ab2 + vip3A(a) + cp4 epsps + dmo + bar Herbicide tolerance and lepidopteran insect resistance
9. 281-24-236 × 3006-210-23 × COT102 Dow AgroSciences LLC Brazil (2018) 1 Not available cry1Ac + vip3A(a) + cry1F Lepidopteran insect resistance
10. 281-24-236 × 3006-210-23 × COT102 × 81910 Dow AgroSciences LLC Brazil (2019), Japan (2016) 2 Not available cry1Ac + vip3A(a) + cry1F + pat + aad-12 Herbicide tolerance and Insect resistance
11. 3006-210-23 × 281-24-236 × MON88913 × COT102 × 81910 Dow AgroSciences LLC Japan (2015), Mexico (2016), South Korea (2017) 3 Not available cry1Ac + vip3A(a) + cry1F + cp4 epsps + pat + aad-12 Herbicide tolerance and Insect resistance
12. GHB811 × T304-40 × GHB119 × COT102 BASF and Bayer Crop Science Brazil (2016) 1 Not available cry1Ab + cry2Ae + vip3A(a) + hppdPF W336 + pat Herbicide tolerance and lepidopteran insect resistance
13. T304-40 × GHB119 × COT102 Bayer Crop Science Brazil (2018) 1 Not available cry1Ab + cry2Ae + vip3A(a) + bar Herbicide tolerance and lepidopteran insect resistance

Compiled from ISAAA GM Approval Database (http://www.isaaa.org/gmapprovaldatabase).