Table 2.
Comparisons of the clinical characteristics between glaucoma progression and nonprogression groups during pregnancy without medication.
| Progression (N = 19) |
Non-Progression (N = 48) |
p Value | |
|---|---|---|---|
| Age | 32.21 ± 2.04 | 32.48 ± 3.25 | 0.97 |
| Number of pre-pregnancy medications | 0.16 ± 0.38 | 0.06 ± 0.25 | 0.22 |
| Pre-pregnancy IOP (mmHg) | 14.79 ± 2.89 | 13.99 ± 2.38 | 0.25 |
| First trimester IOP (mmHg) | 15.75 ± 3.31 | 13.86 ± 2.15 | 0.02 |
| Second trimester IOP (mmHg) | 16.50 ± 2.80 | 13.62 ± 2.28 | 0.001 |
| Third trimester IOP (mmHg) | 17.67 ± 1.56 | 14.44 ± 3.17 | 0.04 |
| Postpartum IOP (mmHg) | 15.48 ± 2.29 | 14.16 ± 2.61 | 0.06 |
| MD (dB) | −4.52 ± 4.83 | −5.56 ± 5.25 | 0.33 |
| PSD (dB) | 5.15 ± 4.05 | 5.82 ± 4.60 | 0.63 |
| RNFL thickness (µm) | |||
| Average | 74.42 ± 9.73 | 76.02 ± 10.42 | 0.56 |
| Temporal | 64.68 ± 13.77 | 65.43 ± 16.04 | 0.86 |
| Superior | 94.53 ± 20.39 | 95.07 ± 22.28 | 0.93 |
| Nasal | 58.16 ± 11.01 | 60.54 ± 9.15 | 0.41 |
| Inferior | 81.00 ± 16.53 | 82.74 ± 22.52 | 0.78 |
| Diagnosis | 0.08 | ||
| Normal-tension glaucoma | 9 | 35 | |
| Primary open-angle glaucoma | 10 | 13 |
Values are presented as mean ± standard deviation: IOP = intraocular pressure; MD = mean deviation; PSD = pattern standard deviation; RNFL = retinal nerve fiber layer.